Zhoukang Zhuang

Streptomycin‐induced ribosome engineering complemented with fermentation optimization for enhanced production of 10‐membered enediynes tiancimycin‐A and tiancimycin‐D

Zhoukang Zhuang, Chengzhou Jiang, Fan Zhang et al. · Biotechnology and Bioengineering · 2019 · 41 citations

Life Sciences, Biotechnology, Molecular Biology +17

Genome shuffling based on different types of ribosome engineering mutants for enhanced production of 10-membered enediyne tiancimycin-A

Huiming Liu, Chengzhou Jiang, Jing Lin et al. · Applied Microbiology and Biotechnology · 2020 · 25 citations

Life Sciences, Biotechnology, Molecular Biology +13

Construction of Inducible Genetic Switch for the Global Regulator WblA To Sustain Both Overproduction of Tiancimycins and On-Demand Sporulation in <i>Streptomyces</i> sp. CB03234

Fan Zhang, Die Gao, Jing Lin et al. · ACS Synthetic Biology · 2020 · 22 citations

Life Sciences, Genetics, Molecular Biology +13

Medium optimization and subsequent fermentative regulation enabled the scaled‐up production of anti‐tuberculosis drug leads ilamycin‐E1/E2

Zhiying Fan, Nian Tong, Zhoukang Zhuang et al. · Biotechnology Journal · 2022 · 12 citations

Life Sciences, Biotechnology, Microbiology +17