Chin-Chun Lu

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate

Mary E. Matyskiela, Suzana S. Couto, Xinde Zheng et al. · Nature Chemical Biology · 2018 · 327 citations

Mutagenesis, Thalidomide-dependent Cereblon Substrate, Biochemistry

Wnt–Ryk signalling mediates medial–lateral retinotectal topographic mapping

Adam M. Schmitt, Jun Shi, Alex M. Wolf et al. · Nature · 2005 · 298 citations

Signal Transduction, Signaling Pathway, Ophthalmology +5

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Mary E. Matyskiela, Weihong Zhang, Hon‐Wah Man et al. · Journal of Medicinal Chemistry · 2017 · 283 citations · Full text

Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract

Yaobo Liu, Jun Shi, Chin-Chun Lu et al. · Nature Neuroscience · 2005 · 266 citations

Developmental Biology, Neuroanatomy, Ryk-mediated Wnt Repulsion +5