Helen Musther

Animal versus human oral drug bioavailability: Do they correlate?

Helen Musther, Andrés Olivares‐Morales, Oliver Hatley et al. · European Journal of Pharmaceutical Sciences · 2013 · 202 citations · Full text

Oral Bioavailability, Preclinical Drug Evaluation, Bioavailability Calculations +13

The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model

Helen Musther, Matthew D. Harwood, Jiansong Yang et al. · Journal of Pharmaceutical Sciences · 2017 · 30 citations · Full text

Mechanobiology, Strain-specific Physiologically, Pharmacokinetic Rat Model +10

Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site

Helen Musther, Katherine L. Gill, Manoranjenni Chetty et al. · The AAPS Journal · 2015 · 22 citations · Full text

Right Cmax, Pharmacotherapy, Pbpk Models +17

Non-specific binding of compounds in <i>in vitro</i> metabolism assays: a comparison of microsomal and hepatocyte binding in different species and an assessment of the accuracy of prediction models

Iain Gardner, Mandy Xu, Chunyan Han et al. · Xenobiotica · 2022 · 20 citations

Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone, and Muscle Tissues

Pieter‐Jan De Sutter, Pieter De Cock, Trevor N. Johnson et al. · Drug Metabolism and Disposition · 2023 · 11 citations · Full text