Sean Neville

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

Dustin S. Siegel, Hon C. Hui, Edward Doerffler et al. · Journal of Medicinal Chemistry · 2017 · 665 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Nucleotide Prodrug GS-5734 Is a Broad-Spectrum Filovirus Inhibitor That Provides Complete Therapeutic Protection Against the Development of Ebola Virus Disease (EVD) in Infected Non-human Primates

Travis K. Warren, Robert Jordan, Michale Lo et al. · Open Forum Infectious Diseases · 2015 · 63 citations · Full text

Pharmacy, Infectious Diseases, Infectious Disease Pharmacotherapy +12

Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial

Chris Parker, Noel W. Clarke, Adrian Cook et al. · The Lancet · 2024 · 49 citations · Full text

Medicine, Oncology, Surgery +15

Development of a Synthetic Process towards a Hepatitis C Polymerase Inhibitor

David Camp, Chris F. Matthews, Sean Neville et al. · Organic Process Research & Development · 2006 · 33 citations

Pharmacy, Chemistry, Medicinal Chemistry +15