Matthias Heidenreich

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

Randall J. Platt, Sidi Chen, Yang Zhou et al. · Cell · 2014 · 2K citations · Full text

Genetic Engineering, Genome Engineering, Gene Editing +4

Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array

Bernd Zetsche, Matthias Heidenreich, Prarthana Mohanraju et al. · Nature Biotechnology · 2016 · 953 citations · Full text

Gene Therapies, Systems Biology, Engineering +10

Optical control of mammalian endogenous transcription and epigenetic states

Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino et al. · Nature · 2013 · 805 citations · Full text

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

Lukasz Swiech, Matthias Heidenreich, Abhishek Banerjee et al. · Nature Biotechnology · 2014 · 784 citations · Full text

Knockout Mouse, Off-target Effect, In Vivo Gene Therapy +11

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

Naomi Habib, Yinqing Li, Matthias Heidenreich et al. · Science · 2016 · 660 citations · Full text