Concepedia

Simone Schierle

SS

12

Publications

278

Citations

11

H-Index

2018

Active since

Affiliations

Goethe University Frankfurt(Current)

Fraunhofer Institute for Translational Medicine and Pharmacology

Fraunhofer Institute for Molecular Biology and Applied Ecology

Simone Schierle is an author at Goethe University Frankfurt specializing in pharmacology, medicine, and drug discovery.

Top concepts

Publications per year

2018–2021

12

Publications

12

Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation

Julius Pollinger, Leonie Gellrich, Simone Schierle et al. · Journal of Medicinal Chemistry · 2019 · 53 citations · Full text

Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology

Simone Schierle, Cathrin Flauaus, Pascal Heitel et al. · Journal of Medicinal Chemistry · 2018 · 37 citations · Full text

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Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics

Simone Schierle, A. Chaikuad, Felix F. Lillich et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors

Felix F. Lillich, Sabine Willems, Xiaomin Ni et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Design and Structural Optimization of Dual FXR/PPARδ Activators

Simone Schierle, Sebastian Neumann, Pascal Heitel et al. · Journal of Medicinal Chemistry · 2020 · 26 citations · Full text

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