Philip V. LoGrasso

Discovery of Potent and Selective Covalent Inhibitors of JNK

Tinghu Zhang, Francisco Iñesta-Vaquera, Mario Niepel et al. · Chemistry & Biology · 2012 · 351 citations · Full text

Medicinal Chemistry, Medicine, Pharmacology +4

Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease

Diego Grassi, Shannon Howard, Minghai Zhou et al. · Proceedings of the National Academy of Sciences · 2018 · 217 citations · Full text

Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation

Jeremy W. Chambers, Philip V. LoGrasso · Journal of Biological Chemistry · 2011 · 188 citations · Full text

Cell Death, Redox Biology, Oxidative Stress +18

The Structure of JNK3 in Complex with Small Molecule Inhibitors

Giovanna Scapin, Sangita B. Patel, JeanMarie Lisnock et al. · Chemistry & Biology · 2003 · 128 citations · Full text

Small Molecule Inhibitors, Protein Assembly, Biochemistry +10

Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow‐Derived Mouse Mesenchymal Stem Cells via a p53‐Dependent Mechanism: Implications for Long‐Term Culture Expansion

Siddaraju V. Boregowda, Veena Krishnappa, Jeremy W. Chambers et al. · Stem Cells · 2012 · 113 citations · Full text

Regenerative Medicine, Developmental Biology, Mouse Mscs +14