Shannon Howard

Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease

Diego Grassi, Shannon Howard, Minghai Zhou et al. · Proceedings of the National Academy of Sciences · 2018 · 217 citations · Full text

Inhibition of JNK Mitochondrial Localization and Signaling Is Protective against Ischemia/Reperfusion Injury in Rats

Jeremy W. Chambers, Alok S. Pachori, Shannon Howard et al. · Journal of Biological Chemistry · 2012 · 79 citations · Full text

Cell Death, Redox Biology, Cellular Physiology +16

Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicity in Vitro and in Vivo

Jeremy W. Chambers, Shannon Howard, Philip V. LoGrasso · Journal of Biological Chemistry · 2012 · 71 citations · Full text

Small Molecule c-jun-N-Terminal Kinase Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson’s Disease

Jeremy W. Chambers, Alok S. Pachori, Shannon Howard et al. · ACS Chemical Neuroscience · 2011 · 69 citations · Full text

Neurochemical Biomarkers, Pharmacotherapy, Molecular Pharmacology +19

Bis-aryl Urea Derivatives as Potent and Selective LIM Kinase (Limk) Inhibitors

Yan Yin, Ke Zheng, Nibal Eid et al. · Journal of Medicinal Chemistry · 2015 · 58 citations · Full text

Drug Target, Selective Lim Kinase, Cellular Pharmacology +21