Mitsuyo Kondo

Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1<i>H</i>-pyrrol-3-yl]-<i>N</i>-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

Yasuyoshi Arikawa, Haruyuki Nishida, Osamu Kurasawa et al. · Journal of Medicinal Chemistry · 2012 · 155 citations

Pharmaceutical Science, Bioorganic Chemistry, Potassium-competitive Acid Blocker +17

Discovery of 1-[2-Fluoro-4-(1<i>H</i>-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1<i>H</i>-pyrazol-5-yl)pyridazin-4(1<i>H</i>)-one (TAK-063), a Highly Potent, Selective, and Orally Active Phosphodiesterase 10A (PDE10A) Inhibitor

Jun Kunitomo, Masato Yoshikawa, Makoto Fushimi et al. · Journal of Medicinal Chemistry · 2014 · 64 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

Discovery of 3-Benzyl-1-(<i>trans</i>-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors

Masahiro Ito, Toshio Tanaka, Akinori Toita et al. · Journal of Medicinal Chemistry · 2018 · 60 citations · Full text

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers

Haruyuki Nishida, Atsushi Hasuoka, Yasuyoshi Arikawa et al. · Bioorganic & Medicinal Chemistry · 2012 · 46 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9

High-Throughput Screening of Potassium-Competitive Acid Blockers

Mitsuyo Kondo, Makiko Kawamoto, Atsushi Hasuoka et al. · SLAS DISCOVERY · 2011 · 28 citations · Full text

Pharmaceutical Science, Chemical Analysis, Prospective Acid Blockers +19