Brooke A. Anderson

Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides

Brooke A. Anderson, Graeme C. Freestone, Audrey Low et al. · Nucleic Acids Research · 2021 · 121 citations · Full text

Dna Gap, Gene Therapies, Novel Therapy +15

Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins

Malwina Hyjek‐Składanowska, Timothy A. Vickers, Agnieszka Napiórkowska-Gromadzka et al. · Journal of the American Chemical Society · 2020 · 88 citations

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Aaron W. Feldman, Vivian T. Dien, Rebekah J. Karadeema et al. · Journal of the American Chemical Society · 2019 · 67 citations · Full text

Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair

Michael P. Ledbetter, Jonathan M. Craig, Rebekah J. Karadeema et al. · Journal of the American Chemical Society · 2020 · 37 citations · Full text

Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA

Sujay P. Sau, Andreas S. Madsen, Peter Podbevšek et al. · The Journal of Organic Chemistry · 2013 · 32 citations

Original Invader Lnas, Genetics, Dna Analysis +26