Frank W. Byers

Selective Activation of M₄Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Michael Bubser, Thomas M. Bridges, Ditte Dencker et al. · ACS Chemical Neuroscience · 2014 · 155 citations · Full text

Medicine, Neuroscience, Pharmacology +17

The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease

Zixiu Xiang, Analisa D. Thompson, John T. Brogan et al. · ACS Chemical Neuroscience · 2011 · 99 citations · Full text

Pharmacy, Neuroscience, Pharmacology +17

Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents

Julie L. Engers, Alice L. Rodriguez, Leah C. Konkol et al. · Journal of Medicinal Chemistry · 2015 · 68 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of (<i>R</i>)-(2-Fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-Hydroxypiperidin-1-yl)methanone (ML337), An mGlu₃ Selective and CNS Penetrant Negative Allosteric Modulator (NAM)

Cody J. Wenthur, Ryan D. Morrison, Andrew S. Felts et al. · Journal of Medicinal Chemistry · 2013 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Partial mGlu5 Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects

Robert W. Gould, Russell J. Amato, Michael Bubser et al. · Neuropsychopharmacology · 2015 · 43 citations

Medicine, Neuroscience, Pharmacology +12