Elizabeth Freilich

In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

Zeyu Chen, Eri Arai, Omar Khan et al. · Cell · 2021 · 218 citations · Full text

Life Sciences, Genetics, Immunology +10

High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening

Rodrigo A. Gier, Krista A. Budinich, Niklaus H. Evitt et al. · Nature Communications · 2020 · 144 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers

Josephine R. Giles, Sasikanth Manne, Elizabeth Freilich et al. · Immunity · 2022 · 122 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

In vitro modeling of CD8 ⁺ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40

Jennifer E. Wu, Sasikanth Manne, Shin Foong Ngiow et al. · Science Immunology · 2023 · 93 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells

Amy E. Baxter, Hua Huang, Josephine R. Giles et al. · Immunity · 2023 · 77 citations

Life Sciences, Genetics, Molecular Biology +15