Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

Hua Huang, Fang Sun, David M. Owen, +4

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyViral HepatitisHcv Replication ComplexBiochemistry +15

Identification of FBL2 As a Geranylgeranylated Cellular Protein Required for Hepatitis C Virus RNA Replication

Chunfu Wang, Michael Gale, Brian C. Keller, +4

Molecular Cell

Viral ReplicationViral HepatitisNatural SciencesMolecular BiologyHepatitis +7

Morbidity and Mortality of Laparoscopic vs Open Total Gastrectomy for Clinical Stage I Gastric Cancer

Fenglin Liu, Chang‐Ming Huang, Zekuan Xu, +15

JAMA Oncology

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, +17

Nature Immunology

ChromatinFunctional GenomicsSingle Cell SequencingMedicineGenetics +10

Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor

David M. Owen, Hua Huang, Ye Jin, +1

Virology

Apolipoprotein EHepatologyHepatitis CMolecular VirologyViral Hepatitis +11

In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

Zeyu Chen, Eri Arai, Omar Khan, +25

Cell

Genome SurgeryImmunologyGene EditingCrisprOff-target Effect +3

Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers

Josephine R. Giles, Sasikanth Manne, Elizabeth Freilich, +19

Immunity

ChromatinTranscriptional RegulationFunctional GenomicsEpigenetic ChangeGenetics +6

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis

Jianwei Xu, Tianxiao Wang, Zhe Cao, +7

Oncotarget

EngineeringPathologyCancer BiologyTumor BiologyDrug Resistance +15

DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

Bin Zhu, Junjie Chen, Ying Feng, +5

Journal of Experimental & Clinical Cancer Research

Nanoenabled Reversal of IDO1-Mediated Immunosuppression Synergizes with Immunogenic Chemotherapy for Improved Cancer Therapy

Hua Huang, Cheng‐Tao Jiang, Song Shen, +8

Nano Letters