Krista A. Budinich

High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening

Rodrigo A. Gier, Krista A. Budinich, Niklaus H. Evitt et al. · Nature Communications · 2020 · 132 citations · Full text

The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

Lisa Cucolo, Qingzhou Chen, Jingya Qiu et al. · Immunity · 2022 · 85 citations · Full text

Tumor Biology, Cancer Immunosurveillance, Medicine +12

Genetic screening for single-cell variability modulators driving therapy resistance

Eduardo A. Torre, Eri Arai, Sareh Bayatpour et al. · Nature Genetics · 2021 · 74 citations · Full text

Genetic Analysis, Allelic Variant, Genetics +3

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

Zhendong Cao, Krista A. Budinich, Hua Huang et al. · Molecular Cell · 2021 · 62 citations · Full text

Hematological Malignancy, Chromatin, Transcriptional Regulation +9

Condensate-Promoting ENL Mutation Drives Tumorigenesis <i>In Vivo</i> Through Dynamic Regulation of Histone Modifications and Gene Expression

Yiman Liu, Qinglan Li, Lele Song et al. · Cancer Discovery · 2024 · 16 citations · Full text

Histone Modifications, Mixed-phenotype Acute Leukemia, Epigenetic Change +21