Paul F. Mercer

Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury

Chris J. Scotton, Malvina A. Krupiczojc, Mélanie Königshoff et al. · Journal of Clinical Investigation · 2009 · 318 citations · Full text

Veterinary Medicine, Molecular Biology, Pathobiology +13

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Hannah V. Woodcock, Jessica Eley, Delphine Guillotin et al. · Nature Communications · 2018 · 226 citations · Full text

Life Sciences, Molecular Biology, Pathobiology +17

Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF

Paul F. Mercer, Hannah V. Woodcock, Jessica Eley et al. · Thorax · 2016 · 206 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

Diminished Prostaglandin E2 Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis

Toby M. Maher, Iona Evans, Stephen E. Bottoms et al. · American Journal of Respiratory and Critical Care Medicine · 2010 · 189 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β ₁ –induced collagen biosynthesis

Brintha Selvarajah, Ilan Azuelos, Manuela Platé et al. · Science Signaling · 2019 · 171 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13