Hannah V. Woodcock

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Hannah V. Woodcock, Jessica Eley, Delphine Guillotin et al. · Nature Communications · 2018 · 226 citations · Full text

Life Sciences, Molecular Biology, Pathobiology +17

Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF

Paul F. Mercer, Hannah V. Woodcock, Jessica Eley et al. · Thorax · 2016 · 206 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Chris Johnston, Danielle J. Smyth, Ravindra Kodali et al. · Nature Communications · 2017 · 201 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β ₁ –induced collagen biosynthesis

Brintha Selvarajah, Ilan Azuelos, Manuela Platé et al. · Science Signaling · 2019 · 171 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis

Pauline T. Lukey, Stephen A. Harrison, Shuying Yang et al. · European Respiratory Journal · 2019 · 145 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +16