Johanna Shen

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Matthew B. Dong, Guangchuan Wang, Ryan D. Chow et al. · Cell · 2019 · 327 citations · Full text

Life Sciences, Genetics, Immunology +16

A web tool for the design of prime-editing guide RNAs

Ryan D. Chow, Jennifer Chen, Johanna Shen et al. · Nature Biomedical Engineering · 2020 · 164 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +13

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks

Ann-Marie K. Shorrocks, Samuel E. Jones, Kaima Tsukada et al. · Nature Communications · 2021 · 90 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering

Kaiyuan Tang, Liqun Zhou, Xiaolong Tian et al. · Nature Biomedical Engineering · 2025 · 23 citations · Full text

Life Sciences, Biotechnology, Molecular Genetics +17