Eva Vidacs

Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight et al. · Cell Reports · 2013 · 135 citations · Full text

Medicine, Oncology, Pharmacology +17

The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia

Adele Baker, Gareth P. Gregory, Inge Verbrugge et al. · Cancer Research · 2015 · 119 citations

Life Sciences, Molecular Biology, Oncology +17

BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members

Simon J. Hogg, Andrea Newbold, Stephin J. Vervoort et al. · Molecular Cancer Therapeutics · 2016 · 73 citations · Full text

Medicine, Cancer Biology, Oncology +17

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Geoffrey M. Matthews, Parinaz Mehdipour, Leonie A. Cluse et al. · Blood · 2015 · 60 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma

Geoffrey M. Matthews, Marcus Lefebure, Maria Doyle et al. · Cell Death and Disease · 2013 · 47 citations · Full text

Medicine, Oncology, Pharmacology +17