Andrea Newbold

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell, David J. Leaver, S.J. Hermans et al. · Nature · 2018 · 300 citations · Full text

Cancer Research, Chromatin, Tumour Growth +12

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin et al. · Cell · 2021 · 208 citations · Full text

Cancer Research, Signal Transduction, Signaling Pathway +9

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

Ralph K. Lindemann, Andrea Newbold, Kate F. Whitecross et al. · Proceedings of the National Academy of Sciences · 2007 · 198 citations · Full text

Immunology, Pathology, Cell Death +18

A Central Role for Bid in Granzyme B-induced Apoptosis

Nigel J. Waterhouse, Karin Sedelies, Kylie A. Browne et al. · Journal of Biological Chemistry · 2004 · 128 citations · Full text

Mitophagy, Central Role, Mitochondrial Function +14

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

Leigh Ellis, Michael Bots, Ralph K. Lindemann et al. · Blood · 2009 · 112 citations · Full text