Gareth P. Gregory

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Adriana E. Tron, Matthew A. Belmonte, Ammar Adam et al. · Nature Communications · 2018 · 479 citations · Full text

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin et al. · Cell · 2021 · 208 citations · Full text

Cancer Research, Signal Transduction, Signaling Pathway +9

Mosunetuzumab Induces Complete Remissions in Poor Prognosis Non-Hodgkin Lymphoma Patients, Including Those Who Are Resistant to or Relapsing After Chimeric Antigen Receptor T-Cell (CAR-T) Therapies, and Is Active in Treatment through Multiple Lines

Stephen J. Schuster, Nancy L. Bartlett, Sarit Assouline et al. · Blood · 2019 · 179 citations

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Zheng Fan, Jennifer R. Devlin, Simon J. Hogg et al. · Science Advances · 2020 · 158 citations · Full text

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Simon J. Hogg, Olga Motorna, Leonie A. Cluse et al. · Molecular Cell · 2021 · 157 citations · Full text