Fiona J. Coutinho

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

Xiaoyang Lan, David J. Jörg, Florence M.G. Cavalli et al. · Nature · 2017 · 418 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

Xin Chen, Siyi Wanggou, Ankur Bodalia et al. · Neuron · 2018 · 410 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Laura M. Richards, Owen Whitley, Graham MacLeod et al. · Nature Cancer · 2021 · 328 citations

Medicine, Neuroscience, Oncology +16

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

Robert J. Vanner, Marc Remke, Marco Gallo et al. · Cancer Cell · 2014 · 310 citations · Full text

Medicine, Cancer Biology, Oncology +12

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

Graham MacLeod, Danielle Bozek, Nishani Rajakulendran et al. · Cell Reports · 2019 · 247 citations · Full text

Medicine, Genetics, Oncology +17