Molecular subgroups of medulloblastoma: the current consensus

Michael D. Taylor, Paul A. Northcott, Andrey Korshunov, +13

Acta Neuropathologica

BiologyNeuro-oncologyMain SubgroupsProtistTumor Heterogeneity +10

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Florence M.G. Cavalli, Marc Remke, Ladislav Rampášek, +91

Cancer Cell

BiologyNeuro-oncologyTumor HeterogeneityMedicineSurgical Pathology +5

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak, +107

Cell

Neuro-oncologyMolecular ClassificationCerebral OrganoidNeurologyNeuroscience +6

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

Paul A. Northcott, David Shih, John Peacock, +131

Nature

GeneticsGenomicsCancer BiologyTumor BiologyNeuro-oncology +21

Dissecting the genomic complexity underlying medulloblastoma

David Jones, Natalie Jäger, Marcel Kool, +84

Nature

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

Tobias Rausch, David Jones, Marc Zapatka, +48

Cell

Dna SequencingSomatic VariantTumor HeterogeneityGeneticsDna Replication +6

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

Marcel Kool, David Jones, Natalie Jäger, +73

Cancer Cell

Tumor HeterogeneityMedicineGeneticsSmoothened InhibitionNext-generation Sequencing +6

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Paul A. Northcott, Catherine Lee, Thomas Zichner, +75

Nature

Oncogenic AgentGeneticsCancer GeneticsGene ExpressionMedicine +2

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

Stephen C. Mack, Hendrik Witt, Rosario M. Piro, +86

Nature

Developmental AnomalyEpigenomic AlterationsDevelopmental BiologyGenetic DisorderMedicine +6

Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma

Hendrik Witt, Stephen C. Mack, Marina Ryzhova, +31

Cancer Cell

Posterior Fossa EpendymomaSurgical PathologyPathologyMolecularly Distinct SubgroupsMedicine