Steven V. Molinski

VX-809 and Related Corrector Compounds Exhibit Secondary Activity Stabilizing Active F508del-CFTR after Its Partial Rescue to the Cell Surface

Paul D. W. Eckford, Mohabir Ramjeesingh, Steven V. Molinski et al. · Chemistry & Biology · 2014 · 105 citations

<scp>O</scp> rkambi® and amplifier co‐therapy improves function from a rare <i> <scp>CFTR</scp> </i> mutation in gene‐edited cells and patient tissue

Steven V. Molinski, Saumel Ahmadi, Wan Ip et al. · EMBO Molecular Medicine · 2017 · 105 citations · Full text

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

Saumel Ahmadi, Zoltán Bozóky, Michelle Di Paola et al. · npj Genomic Medicine · 2017 · 89 citations · Full text

Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site

Steven V. Molinski, Vijay Shahani, Adithya S. Subramanian et al. · Proteins Structure Function and Bioinformatics · 2018 · 60 citations

Structural Bioinformatics, Biomolecular Structure Prediction, Genetics +18

Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains

Onofrio Laselva, Steven V. Molinski, Valeria Casavola et al. · Molecular Pharmacology · 2018 · 58 citations · Full text