Vijay Shahani

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

Sina Haftchenary, H. Artee Luchman, Andriana O. Jouk et al. · ACS Medicinal Chemistry Letters · 2013 · 125 citations · Full text

High-grade Gliomas, Treating Glioblastoma, Cancer Biology +21

Disruption of Transcriptionally Active Stat3 Dimers with Non‐phosphorylated, Salicylic Acid‐Based Small Molecules: Potent in vitro and Tumor Cell Activities

Steven Fletcher, Jardeep Singh, Xiaolei Zhang et al. · ChemBioChem · 2009 · 86 citations · Full text

Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site

Steven V. Molinski, Vijay Shahani, Adithya S. Subramanian et al. · Proteins Structure Function and Bioinformatics · 2018 · 60 citations

Structural Bioinformatics, Biomolecular Structure Prediction, Genetics +18

Concise access to N9-mono-, N2-mono- and N2,N9-di-substituted guanines via efficient Mitsunobu reactions

Steven Fletcher, Vijay Shahani, Alan J. Lough et al. · Tetrahedron · 2010 · 54 citations

Cross-coupling Reaction, Engineering, N9-di-substituted Guanines +6

Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity

Julie L. Lukkarila, Sara R. da Silva, Mohsin Ali et al. · ACS Medicinal Chemistry Letters · 2011 · 41 citations

Molecular Biology, Leukemia Cells, Pharmaceutical Chemistry +16