Garth A. Kinberger

Single-Stranded siRNAs Activate RNAi in Animals

Walt F. Lima, Thazha P. Prakash, Heather Murray et al. · Cell · 2012 · 257 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′<i>O</i>-Methoxyethyl and 2′,4′-Constrained 2′<i>O</i>-Ethyl Nucleic Acid Analogues

Punit P. Seth, Guillermo Vasquez, Charles A. Allerson et al. · The Journal of Organic Chemistry · 2010 · 211 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Potent inhibition of microRNA in vivo without degradation

Scott Davis, Stephanie Propp, Susan M. Freier et al. · Nucleic Acids Research · 2008 · 196 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

Michael Tanowitz, Lisa Hettrick, Alexey S. Revenko et al. · Nucleic Acids Research · 2017 · 160 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Comprehensive Structure–Activity Relationship of Triantennary<i>N</i>-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Thazha P. Prakash, Jinghua Yu, Michael T. Migawa et al. · Journal of Medicinal Chemistry · 2016 · 131 citations

Pharmacy, Pharmaceutics, Pharmacology +12