Mairead Young

Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity

Diane H. Boschelli, Fei Ye, Yanong D. Wang et al. · Journal of Medicinal Chemistry · 2001 · 220 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Rapid Cloning and Heterologous Expression of the Meridamycin Biosynthetic Gene Cluster Using a Versatile <i>Escherichia coli−Streptomyces</i> Artificial Chromosome Vector, pSBAC

Hongbo Liu, Hao Jiang, Bradley Haltli et al. · Journal of Natural Products · 2009 · 62 citations

Life Sciences, Biotechnology, Molecular Biology +17

Hybrid Inhibitors of Phosphatidylinositol 3-Kinase (PI3K) and the Mammalian Target of Rapamycin (mTOR): Design, Synthesis, and Superior Antitumor Activity of Novel Wortmannin−Rapamycin Conjugates

Semiramis Ayral‐Kaloustian, Jianxin Gu, Judy Lucas et al. · Journal of Medicinal Chemistry · 2009 · 47 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Structure–Activity Relationships of Ring-Opened 17-Hydroxywortmannins: Potent Phosphoinositide 3-Kinase Inhibitors with Improved Properties and Anticancer Efficacy

Arie Zask, Joshua A. Kaplan, Lourdes Toral‐Barza et al. · Journal of Medicinal Chemistry · 2008 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT_1A Antagonist

Antonia A. Nikitenko, Deborah A. Evrard, Annmarie L. Sabb et al. · Organic Process Research & Development · 2007 · 25 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12