Jason Z. Zhang

De novo design of luciferases using deep learning

Hsien‐Wei Yeh, Christoffer Norn, Yakov Kipnis et al. · Nature · 2023 · 397 citations · Full text

Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling

Jason Z. Zhang, Tsan-Wen Lu, Lucas M. Stolerman et al. · Cell · 2020 · 316 citations · Full text

Signal Transduction, Cell Regulation, Molecular Regulation +12

An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice

Jinfan Zhang, Bian Liu, Ingie Hong et al. · Nature Chemical Biology · 2020 · 108 citations · Full text

Signal Transduction, Engineering, Awake Mice +14

Designed endocytosis-inducing proteins degrade targets and amplify signals

Buwei Huang, Mohamad H. Abedi, Green Ahn et al. · Nature · 2024 · 97 citations · Full text

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

Early Strategies, Antimicrobial Susceptibility, Health Sciences +13