Jason Z. Zhang

De novo design of luciferases using deep learning

Hsien‐Wei Yeh, Christoffer Norn, Yakov Kipnis et al. · Nature · 2023 · 451 citations · Full text

Life Sciences, Bioengineering, Molecular Biology +17

Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling

Jason Z. Zhang, Sohum Mehta, Jin Zhang et al. · Cell · 2020 · 329 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 7: Highly soluble and in vivo active quaternary ammonium analogue D13-9001, a potential preclinical candidate

Ken‐ichi Yoshida, Ken‐ichi Yoshida, Kiyoshi Nakayama et al. · Bioorganic & Medicinal Chemistry · 2007 · 130 citations

Life Sciences, Microbiology, Pharmacology +16

Designed endocytosis-inducing proteins degrade targets and amplify signals

Buwei Huang, Mohamad H. Abedi, Green Ahn et al. · Nature · 2024 · 122 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

Pharmacy, Microbiology, Pharmacology +17