Yakov Kipnis

De novo design of luciferases using deep learning

Hsien‐Wei Yeh, Christoffer Norn, Yakov Kipnis et al. · Nature · 2023 · 451 citations · Full text

Life Sciences, Bioengineering, Molecular Biology +17

Improving Protein Expression, Stability, and Function with ProteinMPNN

Kiera H. Sumida, Reyes Núñez‐Franco, Indrek Kalvet et al. · Journal of the American Chemical Society · 2024 · 302 citations · Full text

Engineering, Bioinformatics, Biotechnology +17

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

Sagar D. Khare, Yakov Kipnis, Per Greisen et al. · Nature Chemical Biology · 2012 · 210 citations

Life Sciences, Biochemistry, Chemistry +16

Computational design of serine hydrolases

Anna Lauko, Samuel J. Pellock, Kiera H. Sumida et al. · Science · 2025 · 178 citations · Full text

Engineering, Biochemistry, Chemistry +17

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

Anindya Roy, Lei Shi, Ashley Chang et al. · Nature Communications · 2023 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16