David J. Huggins - Concepedia

Author

David J. Huggins

Also Known As

D Huggins, D. Huggins, D. J. Huggins, D.J. Huggins, David Huggins, David J Huggins, David J. Huggins, David J. Huggins, Huggins, David J, Huggins, David John.

107

Publications

3.1K

Citations

H-Index

Concepts

All Affiliations

Cornell University University of Cambridge Tri-Institutional Therapeutics Discovery Institute Weill Cornell Medicine Hutchison/MRC Research Centre

About

David J. Huggins is an author at Cornell University specializing in biochemistry, biophysics, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	493
2	Natural Sciences	11	11	628
3	Engineering	10	10	446
4	Health Sciences	1	1	53
5	Applied Physics	1	1	22

David J. Huggins

Publications

2.3K

Citations

H-Index

Page 1

	Year	Citations
Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch, Nature Communications	2021	180
Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity David J. Huggins, Philip C. Biggin, Marc A. Dämgen, Wiley Interdisciplinary Reviews Computational Molecular Science Biophysical ModelingEngineeringMolecular DynamicsMolecular DesignDrug Resistance	2018	179
PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair Hanan Khoury-Haddad, Noga Guttmann‐Raviv, Inbal Ipenberg, Proceedings of the National Academy of Sciences Dna DamageEpigenetic ChangeMolecular BiologyKdm4d Histone DemethylaseHistone Demethylases	2014	148
A role for glycine in the gating of plant NMDA‐like receptors Christian Dubos, David J. Huggins, Guy H. Grant, The Plant Journal	2003	112
Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations Wei Chen, Di Cui, Steven V. Jerome, Journal of Chemical Information and Modeling	2023	110
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2 M. Janecek, Maxim Rossmann, Pooja Sharma, Scientific Reports	2016	91
On-demand male contraception via acute inhibition of soluble adenylyl cyclase Melanie Balbach, Thomas Rossetti, Jacob Ferreira, Nature Communications	2023	72
Quantifying the Entropy of Binding for Water Molecules in Protein Cavities by Computing Correlations David J. Huggins Biophysical Journal	2015	70
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells Edouard Mullarky, Jiayi Xu, Anita D. Robin, Bioorganic & Medicinal Chemistry Letters Serine SynthesisIndole AmidesBiosynthesisAldo-keto ReductaseBiochemistry	2019	65
Correlations in liquid water for the TIP3P-Ewald, TIP4P-2005, TIP5P-Ewald, and SWM4-NDP models David J. Huggins The Journal of Chemical Physics	2012	64

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