David J. Huggins

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues

Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch et al. · Nature Communications · 2021 · 180 citations · Full text

Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity

David J. Huggins, Philip C. Biggin, Marc A. Dämgen et al. · Wiley Interdisciplinary Reviews Computational Molecular Science · 2018 · 179 citations · Full text

Biophysical Modeling, Engineering, Molecular Dynamics +23

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

Hanan Khoury-Haddad, Noga Guttmann‐Raviv, Inbal Ipenberg et al. · Proceedings of the National Academy of Sciences · 2014 · 148 citations · Full text

Dna Damage, Epigenetic Change, Molecular Biology +16

A role for glycine in the gating of plant NMDA‐like receptors

Christian Dubos, David J. Huggins, Guy H. Grant et al. · The Plant Journal · 2003 · 112 citations · Full text

Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations

Wei Chen, Di Cui, Steven V. Jerome et al. · Journal of Chemical Information and Modeling · 2023 · 110 citations