TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss, +95

Nature

TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

Martina Hallegger, Anob M. Chakrabarti, Flora Lee, +14

Cell

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition

Miha Modic, Markus Grosch, Gregor Rot, +17

Molecular Cell

Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells

Maria Dermit, Martin Dodel, Flora Lee, +6

Developmental Cell

Subcellular Mrna LocalizationNatural SciencesRibosomal Protein-coding MrnasCancer GrowthCell-matrix Interaction +10

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

Anaïs Bellon, Archana Iyer, Simone Bridi, +12

Cell Reports

Subcytoplasmic location of translation controls protein output

Ellen L. Horste, Mervin M. Fansler, Ting Cai, +6

Molecular Cell

An improved iCLIP protocol

Flora Lee, Anob M. Chakrabarti, Heike Hänel, +11

EngineeringGeneticsMolecular BiologyTranscriptomics TechnologyGenomics +21

Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior

Lorenza Magno, Zeinab Asgarian, Valentina Pendolino, +9

Cell Reports

Cortical Network MaturationDevelopmental Cognitive NeuroscienceBrain MechanismNeurodevelopmentCellular Neurobiology +19

HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion

Julie Qiaojin Lin, Deepak Khuperkar, Sofia Pavlou, +12

The EMBO Journal

Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization

Anna‐Leigh Brown, Oscar G. Wilkins, Matthew J. Keuss, +20

NeurogenomicsTdp-43 BindingGeneticsPathologyNeurochemical Biomarkers +21