Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

Maheshwor Timilshina, Zhiwei You, Sonja M. Lacher, +16

Cell Reports

Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation

Shobha Regmi, Shiva Pathak, Mahesh R. Nepal, +10

Journal of Controlled Release

InflammationChronic Inflammatory DiseasesDendritic Cell MigrationAnti-inflammatoryMedicine +7

Pharmacokinetic Interaction of Chrysin with Caffeine in Rats

Keumhan Noh, Do Gyeong Oh, Mahesh R. Nepal, +6

Biomolecules & Therapeutics

Chrysin SulfatePharmacological StudyBiochemistryMedicinePhysiology +12

Engineering “cell-particle hybrids” of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation

Tiep Tien Nguyen, Tung Thanh Pham, Hanh Thuy Nguyen, +12

Biomaterials

Tissue EngineeringRegenerative MedicineIslet TransplantationCell-based Drug DeliveryPancreatic Islets +11

Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-<i>b</i>]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic Agents for Breast Cancer

Tara Man Kadayat, Seojeong Park, Aarajana Shrestha, +13

Journal of Medicinal Chemistry

Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation

Tiep Tien Nguyen, Duc‐Vinh Pham, Junhyeung Park, +20

Science Advances

Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats

Keumhan Noh, Mahesh R. Nepal, Ki Sun Jeong, +8

Biomolecules & Therapeutics

Medicinal ChemistryPolyphenolicsPharmacological StudyBiochemistryMedicine +13

Effects of Intestinal Microbiota on Pharmacokinetics of Crocin and Crocetin in Male Sprague-Dawley Rats

Rajina Shakya, Mahesh R. Nepal, Mi Jeong Kang, +1

Metabolites

Role of Intestinal Microbiota in Metabolism of Gastrodin In Vitro and In Vivo

Mahesh R. Nepal, Ki Sun Jeong, Geon Ho Kim, +3

Metabolites

A simple in chemico method for testing skin sensitizing potential of chemicals using small endogenous molecules

Mahesh R. Nepal, Rajina Shakya, Mi Jeong Kang, +1

Toxicology Letters

MedicineAnalytical ChemistryToxicologySmall Endogenous MoleculesChemical Agent +6