Enhanced viability and function of mesenchymal stromal cell spheroids is mediated <i>via</i> autophagy induction

Shobha Regmi, Pawan Kumar Raut, Shiva Pathak, +3

Autophagy

Tissue adhesive FK506–loaded polymeric nanoparticles for multi–layered nano–shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model

Tung Thanh Pham, Tiep Tien Nguyen, Shiva Pathak, +13

Biomaterials

Tissue EngineeringXenograft SurvivalPancreatic IsletsEngineeringTherapeutic Nanomaterials +6

Hyaluronic acid-capped compact silica-supported mesoporous titania nanoparticles for ligand-directed delivery of doxorubicin

Biki Gupta, Bijay Kumar Poudel, Hima Bindu Ruttala, +9

Acta Biomaterialia

NanoparticlesNanomedicineLigand-directed DeliveryEngineeringNanomaterials +6

Development of Bioactive PEGylated Nanostructured Platforms for Sequential Delivery of Doxorubicin and Imatinib to Overcome Drug Resistance in Metastatic Tumors

Biki Gupta, Thiruganesh Ramasamy, Bijay Kumar Poudel, +10

ACS Applied Materials & Interfaces

EngineeringMetastatic TumorsBiomedical EngineeringSequential DeliveryTumor Biology +18

Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation

Shobha Regmi, Shiva Pathak, Mahesh R. Nepal, +10

Journal of Controlled Release

InflammationChronic Inflammatory DiseasesDendritic Cell MigrationAnti-inflammatoryMedicine +7

Polymeric microsphere-facilitated site-specific delivery of quercetin prevents senescence of pancreatic islets in vivo and improves transplantation outcomes in mouse model of diabetes

Shiva Pathak, Shobha Regmi, Tiep Tien Nguyen, +12

Acta Biomaterialia

Tissue EngineeringRegenerative MedicineIslet TransplantationQuercetin Prevents SenescencePancreatic Islets +12

Targeted delivery of doxorubicin for the treatment of bone metastasis from breast cancer using alendronate-functionalized graphene oxide nanosheets

Tung Thanh Pham, Hanh Thuy Nguyen, Cao Dai Phung, +10

Journal of Industrial and Engineering Chemistry

NanomedicineEngineeringNanomaterialsMedicineTherapeutic Nanomaterials +9

Polyamino Acid Layer-by-Layer (LbL) Constructed Silica-Supported Mesoporous Titania Nanocarriers for Stimuli-Responsive Delivery of microRNA 708 and Paclitaxel for Combined Chemotherapy

Biki Gupta, Hima Bindu Ruttala, Bijay Kumar Poudel, +12

ACS Applied Materials & Interfaces

NanoparticlesNanotherapeuticsEngineeringCombined ChemotherapyPolyamino Acid Layer-by-layer +23

Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration

Shobha Regmi, Yoojin Seo, Ji‐Su Ahn, +10

Biomaterials

InflammationRegenerative MedicineMesenchymal Stem CellsMucosal ImmunologyMedicine +9

Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice

Shiva Pathak, Shobha Regmi, Biki Gupta, +10

Drug Delivery