Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

Jason S. Seidman, Ty D. Troutman, Mashito Sakai, +20

Immunity

ChromatinLineage PlasticityEpigenetic ChangeGeneticsLiver Physiology +8

Commensal-driven immune zonation of the liver promotes host defence

Anita Gola, Michael G. Dorrington, Emily Speranza, +9

Nature

Host ResponseHepatologyMedicineLiver PhysiologyInnate Immune System +5

IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Andrea J. Radtke, Evelyn Kandov, Bradley Lowekamp, +13

Proceedings of the National Academy of Sciences

EngineeringMicroscopyImmunologyPathologyBiomedical Engineering +17

A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells

Harikesh S. Wong, Kyemyung Park, Anita Gola, +10

Cell

Systems BiologySignal TransductionAutoimmune DiseaseImmune HomeostasisSelf-activated T Cells +11

IBEX: an iterative immunolabeling and chemical bleaching method for high-content imaging of diverse tissues

Andrea J. Radtke, Colin J. Chu, Ziv Yaniv, +14

Nature Protocols

Immunocytochemical TechniqueChemical Bleaching MethodHigh-content ImagingMedical ImagingEngineering +11

Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories

Kevin Andrew Uy Gonzales, Lisa Polak, Irina Matos, +11

Science

The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

António P. Baptista, Anita Gola, Yuefeng Huang, +6

Immunity

Immunological MemoryAdaptive Immune SystemT-regulatory CellImmunologyEffective Adaptive Immunity +6

The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via β2 integrins (CD11/CD18)

Ludwig T. Weckbach, Anita Gola, Michael Winkelmann, +10

Blood

Stem cells tightly regulate dead cell clearance to maintain tissue fitness

Katherine Stewart, Merve Deniz Abdusselamoglu, Matthew Tierney, +13

Nature

IBEX – A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Andrea J. Radtke, Evelyn Kandov, Bradley Lowekamp, +13