Ty D. Troutman

TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation

Ricardo A. Irizarry-Caro, Margaret M. McDaniel, Garrett R. Overcast et al. · Proceedings of the National Academy of Sciences · 2020 · 417 citations · Full text

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

Jason S. Seidman, Ty D. Troutman, Mashito Sakai et al. · Immunity · 2020 · 408 citations · Full text

Chromatin, Lineage Plasticity, Epigenetic Change +10

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

Mashito Sakai, Ty D. Troutman, Jason S. Seidman et al. · Immunity · 2019 · 399 citations · Full text

Induced Pluripotent Stem Cell, Developmental Biology, Cell Regulation +8

IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation

Keng-Mean Lin, Wei Hu, Ty D. Troutman et al. · Proceedings of the National Academy of Sciences · 2013 · 282 citations · Full text

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function

Verena M. Link, Sascha H. Duttke, Hyun Bae Chun et al. · Cell · 2018 · 203 citations · Full text

Inflammation, Transcriptional Regulation, Domain-wide Mechanisms +10