Commensal-driven immune zonation of the liver promotes host defence

Anita Gola, Michael G. Dorrington, Emily Speranza, +9

Nature

Host ResponseHepatologyMedicineLiver PhysiologyInnate Immune System +5

IBEX: A versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues

Andrea J. Radtke, Evelyn Kandov, Bradley Lowekamp, +13

Proceedings of the National Academy of Sciences

EngineeringMicroscopyImmunologyPathologyBiomedical Engineering +17

Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys

Emily Speranza, Brandi N. Williamson, Friederike Feldmann, +12

Science Translational Medicine

Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

Xuan Liu, Emily Speranza, César Muñoz‐Fontela, +24

Genome biology

IBEX: an iterative immunolabeling and chemical bleaching method for high-content imaging of diverse tissues

Andrea J. Radtke, Colin J. Chu, Ziv Yaniv, +14

Nature Protocols

Immunocytochemical TechniqueChemical Bleaching MethodHigh-content ImagingMedical ImagingEngineering +11

Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients

Andrea J. Radtke, Ekaterina Postovalova, Arina Varlamova, +38

Cancer Cell

Lymphoid NeoplasiaTissue ArchitectureMulti-omic ProfilingMedicineMulti-omics Study +12

Neuronal maturation reduces the type I IFN response to orthobunyavirus infection and leads to increased apoptosis of human neurons

Clayton W. Winkler, Tyson A. Woods, Bradley R. Groveman, +6

Journal of Neuroinflammation

Comparison of Transcriptomic Platforms for Analysis of Whole Blood from Ebola-Infected Cynomolgus Macaques

Emily Speranza, Louis A. Altamura, Kirsten Kulcsar, +11

Scientific Reports

RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins

Michael L. Piacentino, Daniel T. Zuch, Julie Fishman, +23

Development

Ventral SkeletalCalcium Carbonate SkeletonCellular PhysiologySkeletal PatterningMarine Genomics +14

T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans

Emily Speranza, Paula Ruibal, Julia R. Port, +8

The Journal of Infectious Diseases