Eleanor Williams

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Xueqing Zou, Gene Ching Chiek Koh, Arjun S. Nanda et al. · Nature Cancer · 2021 · 164 citations · Full text

Genome Instability, Medicine, Genetics +11

Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

Jérôme Fortin, Ruxiao Tian, Ida Zarrabi et al. · Cancer Cell · 2020 · 91 citations · Full text

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Ramita Dewan, Ruth Chia, Jinhui Ding et al. · Neuron · 2020 · 79 citations · Full text

Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Pathology +8

Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation

Daniel Horbelt, Jan H. Boergermann, A. Chaikuad et al. · Journal of Biological Chemistry · 2014 · 72 citations · Full text

Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva

Eleanor Williams, Jana Bagarova, Georgina Kerr et al. · JCI Insight · 2021 · 64 citations · Full text

Osteopathy, Bone Repair, Pathology +25