Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Ruth Chia, Marya S. Sabir, Sara Bandrés‐Ciga, +163

Nature Genetics

Neurodegenerative DiseasesAlzheimer's DiseaseGeneticsDementiaGenetic Architecture +6

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Alexandria Beilina, Iakov N. Rudenko, Alice Kaganovich, +160

Proceedings of the National Academy of Sciences

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

Cornelis Blauwendraat, Faraz Faghri, Lasse Pihlstrøm, +38

Neurobiology of Aging

Neurodegenerative DiseasesNeurological DisorderMedicineGeneticsUpdated Version +6

A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation

Bernard M. H. Law, Victoria A. Spain, Veronica H.L. Leinster, +13

Journal of Biological Chemistry

Signal TransductionCell RegulationMolecular RegulationNatural SciencesDirect Interaction +9

Superoxide Dismutase 1 and tgSOD1G93A Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis

Ruth Chia, M. Howard Tattum, Samantha W. Jones, +3

PLoS ONE

Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study

Ruth Chia, Sara Sáez-Atiénzar, Natalie A. Murphy, +60

Proceedings of the National Academy of Sciences

A Test of Static and Dynamic Balance Function in Children With Cochlear Implants

Sharon L. Cushing, Ruth Chia, Adrian L. James, +2

Archives of Otolaryngology - Head and Neck Surgery

The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation

Iakov N. Rudenko, Alice Kaganovich, David N. Hauser, +6

Biochemical Journal

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

Edwin Jabbari, Shunsuke Koga, Rebecca R. Valentino, +53

The Lancet Neurology

Genome-wide Association StudyGenetic DisorderGeneticsGenetic EpidemiologyProgressive Supranuclear Palsy +5

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

Ruth Chia, Sara Haddock, Alexandra Beilina, +7

Nature Communications

Signal TransductionSignaling PathwayMolecular PathwayMedicineNatural Sciences +9