Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia

David Irvine, Bin Zhang, Ross Kinstrie, +12

Scientific Reports

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Anuradha Tarafdar, Lisa Hopcroft, Paolo Gallipoli, +8

Blood

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

James Doonan, Anuradha Tarafdar, Miguel A. Pineda, +6

Nature Communications

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

Jenny Crowe, Felicity E. Lumb, James Doonan, +10

PLoS Pathogens

Anti-agingAgingMicrobial PathogensImmunologyImmune Regulation +24

Distribution, genetic diversity and recombination analysis of Citrus tristeza virus of India

Kajal Kumar Biswas, Anuradha Tarafdar, Subha Diwedi, +1

Virus Genes

Genetic DiversityPlant VirusPlant-virus InteractionGeneticsVirology +8

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

James Doonan, Felicity E. Lumb, Miguel A. Pineda, +6

Frontiers in Immunology

Canonical Wnt Signaling Promotes Early Hematopoietic Progenitor Formation and Erythroid Specification during Embryonic Stem Cell Differentiation

Anuradha Tarafdar, Edwina Dobbin, Pamela M. Corrigan, +2

PLoS ONE

GeneticsStem Cell BiologyCell SpecializationRegenerative MedicineTranscriptional Regulation +22

AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival

Emilio Cosimo, Anuradha Tarafdar, Michael W. Moles, +13

Clinical Cancer Research

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis

Dina Vara, Reiner K. Mailer, Anuradha Tarafdar, +7

Arteriosclerosis Thrombosis and Vascular Biology

Human platelets release amyloid peptides β1-40 and β1-42 in response to hemostatic, immune, and hypoxic stimuli

Nina Wolska, Meral Celikag, Antonio Virgilio Failla, +5

Research and Practice in Thrombosis and Haemostasis