Felicity E. Lumb

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome

Justyna Rzepecka, Miguel A. Pineda, Lamyaa Al‐Riyami et al. · Journal of Autoimmunity · 2015 · 77 citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +17

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

James Doonan, Anuradha Tarafdar, Miguel A. Pineda et al. · Nature Communications · 2019 · 72 citations · Full text

Life Sciences, Immunology, Microbiology +17

The Parasitic Worm Product ES‐62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/<i>lpr</i> Mice

David T. Rodgers, Mairi McGrath, Miguel A. Pineda et al. · Arthritis & Rheumatology · 2014 · 54 citations · Full text

Life Sciences, Immunology, Pathology +17

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

Jenny Crowe, Felicity E. Lumb, James Doonan et al. · PLoS Pathogens · 2020 · 38 citations · Full text

Education, Immunology, Nutritional Sciences +17

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

James Doonan, Felicity E. Lumb, Miguel A. Pineda et al. · Frontiers in Immunology · 2018 · 36 citations · Full text

Medicine, Immunology, Pathobiology +17