Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

Sara Gardenghi, Maria Franca Marongiu, Pedro Luiz Ramos, +15

Blood

Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia

Pedro Luiz Ramos, Carla Casu, Sara Gardenghi, +13

Nature Medicine

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

Sara Gardenghi, Pedro Luiz Ramos, Maria Franca Marongiu, +16

Journal of Clinical Investigation

Iron MetabolismExcessive Iron AbsorptionIron DeficiencyRedox BiologyOxidative Stress +18

Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II

Sai Kuchibhotla, Difernando Vanegas, David J. Kennedy, +4

Cardiovascular Research

Stem Cell Transplantation Reveals That Absence of Macrophage CD36 Is Protective Against Atherosclerosis

Maria Febbraio, Ella Guy, Roy L. Silverstein

Arteriosclerosis Thrombosis and Vascular Biology

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia

I.V. Libani, Ella Guy, Luca Melchiori, +17

Blood

The impact of overexpression and deficiency of fatty acid translocase (FAT)/CD36

Maria Febbraio, Ella Guy, Chris T. Coburn, +4

Molecular and Cellular Biochemistry

Continued inhibition of atherosclerotic lesion development in long term Western diet fed CD36°/apoE° mice

Ella Guy, Sai Kuchibhotla, Roy L. Silverstein, +1

Atherosclerosis

InflammationImmunologyCd36°/apoe° MicePathologyVascular Biology +6

Dietary Cholesterol Plays a Role in CD36-Mediated Atherogenesis in LDLR-Knockout Mice

David J. Kennedy, Sai Kuchibhotla, Ella Guy, +5

Arteriosclerosis Thrombosis and Vascular Biology

Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

Pedro Lima Ramos, Ella Guy, Nan Chen, +8

Blood