Meiyang Xi

Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis

Zhengyu Jiang, Mengchen Lu, Lili Xu et al. · Journal of Medicinal Chemistry · 2014 · 245 citations · Full text

Studies on chemical modification and biology of a natural product, gambogic acid (III): Determination of the essential pharmacophore for biological activity

Xiaojian Wang, Na Lu, Qian Yang et al. · European Journal of Medicinal Chemistry · 2011 · 58 citations

Medicinal Chemistry, Biochemistry, Bioassay-guided Isolation +9

Insight into the Intermolecular Recognition Mechanism between Keap1 and IKKβ Combining Homology Modelling, Protein-Protein Docking, Molecular Dynamics Simulations and Virtual Alanine Mutation

Zhengyu Jiang, Hongxi Chu, Meiyang Xi et al. · PLoS ONE · 2013 · 51 citations · Full text

Crystal Structure, Molecular Regulation, Molecular Biology +20

Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure–Activity Relationship Study

Lili Xu, Junfeng Zhu, Xiaoli Xu et al. · Journal of Medicinal Chemistry · 2015 · 47 citations

Nrf2/are Pathway, Lipid Peroxidation, Hits Identification +20

3-Aroylmethylene-2,3,6,7-tetrahydro-1<i>H</i>-pyrazino[2,1-<i>a</i>]isoquinolin-4(11b<i>H</i>)-ones as Potent Nrf2/ARE Inducers in Human Cancer Cells and AOM-DSS Treated Mice

Meiyang Xi, Jianmin Jia, Haopeng Sun et al. · Journal of Medicinal Chemistry · 2013 · 42 citations · Full text

Chemoprevention Strategy, Immunology, Nrf2 Nuclear Translocation +23