Concepedia

Mengchen Lu

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Publications

31

Citations

1.8K

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22

Active since

2013

Affiliations

China Pharmaceutical University(Current)

State Key Laboratory of Natural Medicine

Chongqing University

Mengchen Lu is an author at China Pharmaceutical University specializing in medicine, biochemistry, and natural sciences.

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Top concepts

Publications per year

2013–2023

31

Publications

31

Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway

Mengchen Lu, Tian Liu, Qiong Jiao et al. · European Journal of Medicinal Chemistry · 2018 · 277 citations · Full text

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Discovery of Potent Keap1–Nrf2 Protein–Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis

Zhengyu Jiang, Mengchen Lu, Lili Xu et al. · Journal of Medicinal Chemistry · 2014 · 245 citations · Full text

Azo-PROTAC: Novel Light-Controlled Small-Molecule Tool for Protein Knockdown

Yuhui Jin, Mengchen Lu, Yan Wang et al. · Journal of Medicinal Chemistry · 2020 · 160 citations

, , +15

CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation

Mengchen Lu, Jing Zhao, Yuting Liu et al. · Redox Biology · 2019 · 135 citations · Full text

An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis

Mengchen Lu, Jianai Ji, Yong-Lin Jiang et al. · Scientific Reports · 2016 · 112 citations · Full text

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