Jianai Ji

Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway

Mengchen Lu, Tian Liu, Qiong Jiao et al. · European Journal of Medicinal Chemistry · 2018 · 277 citations · Full text

Protein Function, Biochemistry, Protein Assembly +11

An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis

Mengchen Lu, Jianai Ji, Yong-Lin Jiang et al. · Scientific Reports · 2016 · 112 citations · Full text

Polar Recognition Group Study of Keap1-Nrf2 Protein–Protein Interaction Inhibitors

Mengchen Lu, Shi-Jie Tan, Jianai Ji et al. · ACS Medicinal Chemistry Letters · 2016 · 34 citations · Full text

ARE-PROTACs Enable Co-degradation of an Nrf2–MafG Heterodimer

Jianai Ji, Sinan Ma, Yuxuan Zhu et al. · Journal of Medicinal Chemistry · 2023 · 31 citations

Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

Mengchen Lu, Jianai Ji, Yifei Lv et al. · Cell chemical biology · 2023 · 16 citations