Matthias Hebben

Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders

Jihad El Andari, Edith Renaud-Gabardos, Warut Tulalamba et al. · Science Advances · 2022 · 92 citations · Full text

Pharmacy, Bioengineering, Biotechnology +13

Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing

Émilie Lecomte, Benoît Tournaire, Benjamin Cogné et al. · Molecular Therapy — Nucleic Acids · 2015 · 77 citations · Full text

Life Sciences, Biology, Molecular Biology +17

Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome

Fanny Collaud, Giulia Bortolussi, Laurence Guianvarc’h et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 61 citations · Full text

Medicine, Molecular Genetics, Molecular Medicine +4

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8

Marti Cabanes‐Creus, Renina Gale Navarro, Erhua Zhu et al. · Molecular Therapy — Methods & Clinical Development · 2021 · 44 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Downstream bioprocessing of AAV vectors: industrial challenges & regulatory requirements

Matthias Hebben · Cell and Gene Therapy Insights · 2018 · 39 citations

Life Sciences, Bioengineering, Biotechnology +17