Concepedia

Author

Giulia Bortolussi

International Centre for Genetic Engineering and BiotechnologyORCID

Also Known As

Bortolussi, Giulia, G Bortolussi, G. Bortolussi, Giulia BORTOLUSSI, Giulia Bortolussi

49

Publications

1K

Citations

19

H-Index

44

Concepts

All Affiliations

International Centre for Genetic Engineering and BiotechnologyGenethon (France)University of AmsterdamInsermFondazione Italiana Fegato
GB

About

Giulia Bortolussi is an author at International Centre for Genetic Engineering and Biotechnology specializing in medicine, immunology, and genome editing.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

191

2

Health Sciences

2

2

64

3

Engineering

1

1

13

4

Natural Sciences

1

1

59

5

Biochemistry

1

1

17

Giulia Bortolussi

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23

Publications

916

Citations

18

H-Index

YearCitations

Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of Crigler–Najjar Syndrome

Giulia Bortolussi, Lorena Zentillin, Jana Vaníková,

Human Gene Therapy

2014

81

Rescue of bilirubin‐induced neonatal lethality in a mouse model of Crigler‐Najjar syndrome type I by AAV9‐mediated gene transfer

Giulia Bortolussi, Lorena Zentilin, Gabriele Baj,

The FASEB Journal

2011

75

Promoterless gene targeting without nucleases rescues lethality of a Crigler‐Najjar syndrome mouse model

Fabiola Porro, Giulia Bortolussi, Adi Barzel,

EMBO Molecular Medicine

2017

61

Gene Therapy in Patients with the Crigler–Najjar Syndrome

Lorenzo D’Antiga, Ulrich Beuers, Giuseppe Ronzitti,

New England Journal of Medicine

2023

61

Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome

Fanny Collaud, Giulia Bortolussi, Laurence Guianvarc’h,

Molecular Therapy — Methods & Clinical Development

2018

59

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases

Alessia De Caneva, Fabiola Porro, Giulia Bortolussi,

JCI Insight

2019

59

A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

Giuseppe Ronzitti, Giulia Bortolussi, Remco van Dijk,

Molecular Therapy — Methods & Clinical Development

2016

58

Bilirubin‐Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double‐Strand Break Repair Pathways in Human Cells

Vipin Rawat, Giulia Bortolussi, Silvia Gazzin,

Oxidative Medicine and Cellular Longevity

2018

58

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model

Simone Vodret, Giulia Bortolussi, Jana Jašprová,

Journal of Neuroinflammation

2017

48

Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia

Simone Vodret, Giulia Bortolussi, Alessandra Iaconcig,

Brain Behavior and Immunity

2018

47

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