Jamal Nasir

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

Jamal Nasir, Stan Floresco, John R. OʼKusky et al. · Cell · 1995 · 861 citations · Full text

Knockout Mouse, Morphological Changes, Developmental Biology +8

A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

John Hodgson, N. Agopyan, Claire‐Anne Gutekunst et al. · Neuron · 1999 · 828 citations · Full text

Neurodegenerative Diseases, Full-length Mutant Huntingtin, Selective Striatal Neurodegeneration +8

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

Collette K. Hand, Hitoshi Osuga, Yoshiko Yanagisawa et al. · Nature Genetics · 2001 · 675 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Genetics +7

Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix

Sabina Sperandio, Karen S. Poksay, Ian de Belle et al. · Cell Death and Differentiation · 2004 · 379 citations · Full text

Signal Transduction, Signaling Pathway, Map Kinases +5

Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

Dita Rasper, John P. Vaillancourt, Vicky M. Houtzager et al. · Cell Death and Differentiation · 1998 · 315 citations · Full text

Cell Death Attenuation, Signal Transduction, Signaling Pathway +10