A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson, +9

Journal of Biological Chemistry

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

Y. Paul Goldberg, Donald W. Nicholson, Dita Rasper, +8

Nature Genetics

Proapoptotic Cysteine ProteaseProtein FunctionBiochemistryNatural SciencesMedicine +6

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Cheryl L. Wellington, Lisa Ellerby, Abigail S. Hackam, +18

Journal of Biological Chemistry

Androgen ReceptorGeneticsApoptosisMolecular BiologyCell Death +15

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

J. Rotonda, Donald W. Nicholson, Kimberly M. Fazil, +9

Nature Structural Biology

Protein FunctionSignal TransductionBiochemistryOrganelle DynamicNatural Sciences +10

Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

Dita Rasper, John P. Vaillancourt, Vicky M. Houtzager, +17

Cell Death and Differentiation

Cell Death AttenuationSignal TransductionSignaling PathwayCell InteractionApoptosis +8

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

François G. Gervais, Roshni R. Singaraja, Steven Xanthoudakis, +11

Nature Cell Biology

Novel Partner HippiHuntingtin-interacting Protein Hip-1Signal TransductionAutoimmune DiseaseSignaling Pathway +5

Purification and catalytic properties of human caspase family members

Margarita García‐Calvo, Erin P. Peterson, Dita Rasper, +4

Cell Death and Differentiation

Protein FunctionProtein ExpressionCellular EnzymologyBiochemistryNatural Sciences +2

The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7

Johannes Maier, Z. Lahoua, Nathalie H. Gendron, +8

Journal of Neuroscience

ApoptosisImmunologyCell DeathCaspases 3Neuroinflammation +14

Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype of<i>Caspase-3</i>-Null Mice

Caroline Houde, Kathleen G. Banks, Nathalie Coulombe, +5

Journal of Neuroscience

Caspase-3-deficient MiceBrain DevelopmentCaspase-7 ExpressionApoptosisImmunology +22

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228

Folkert Reck, Alun Bermingham, Johanne Blais, +35

Bioorganic & Medicinal Chemistry Letters

Antimicrobial Drug DiscoveryAntimicrobial SusceptibilityHealth SciencesAntibioticsAntimicrobial Resistance Gene +10