Brenda R. Flam

Endothelial nitric oxide production is tightly coupled to the citrulline–NO cycle

Brenda R. Flam, Duane C. Eichler, Larry P. Solomonson · Nitric Oxide · 2007 · 132 citations

Biochemistry, Reactive Nitrogen Specie, Medicine +7

Caveolar Localization of Arginine Regeneration Enzymes, Argininosuccinate Synthase, and Lyase, with Endothelial Nitric Oxide Synthase

Brenda R. Flam, Paul J. Hartmann, Melissa Harrell-Booth et al. · Nitric Oxide · 2001 · 104 citations

Caveolar Localization, Argininosuccinate Synthase, Biochemistry +8

TXNIP shuttling: missing link between oxidative stress and inflammasome activation

Troy Lane, Brenda R. Flam, Richard F. Lockey et al. · Frontiers in Physiology · 2013 · 102 citations · Full text

Cell Death, Redox Biology, Cellular Physiology +20

New Azolidinediones as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties

Michael S. Malamas, Janet Sredy, Iwan Gunawan et al. · Journal of Medicinal Chemistry · 2000 · 102 citations · Full text

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications

M.C. Van Zandt, E. Sibley, Erin E. McCann et al. · Bioorganic & Medicinal Chemistry · 2004 · 48 citations

Medicinal Chemistry, Diabetes Management, Aldo-keto Reductase +9