Kohta Toshimitsu

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

Masayuki Fujii, Mariko Shimokawa, Shoichi Date et al. · Cell stem cell · 2016 · 853 citations · Full text

Medicine, Cancer Biology, Oncology +12

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

Takashi Seino, Shintaro Kawasaki, Mariko Shimokawa et al. · Cell stem cell · 2018 · 638 citations

Medicine, Cell Biology, Oncology +14

Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition

Masayuki Fujii, Mami Matano, Kohta Toshimitsu et al. · Cell stem cell · 2018 · 564 citations · Full text

Life Sciences, Biology, Cell Biology +14

Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis

Kosaku Nanki, Kohta Toshimitsu, Ai Takano et al. · Cell · 2018 · 343 citations · Full text

Medicine, Cancer Biology, Oncology +16

Somatic inflammatory gene mutations in human ulcerative colitis epithelium

Kosaku Nanki, Masayuki Fujii, Mariko Shimokawa et al. · Nature · 2019 · 327 citations

Life Sciences, Genetics, Immunology +14