Aimee Fourie-O’Donohue

Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates

Leanna R. Staben, Stefan G. Koenig, Sophie M. Lehar et al. · Nature Chemistry · 2016 · 147 citations

Medicinal Chemistry, Antibody–drug Conjugates, Drug Targeting +8

High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers

Rachana Ohri, Sunil Bhakta, Aimee Fourie-O’Donohue et al. · Bioconjugate Chemistry · 2018 · 109 citations

Molecular Biology, Immunochemistry, Antibody Engineering +16

Site-Specific Trastuzumab Maytansinoid Antibody–Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering

Thomas H. Pillow, Janet Tien, Kathryn Parsons-Reponte et al. · Journal of Medicinal Chemistry · 2014 · 106 citations

Modulating Antibody–Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification

Dian Su, Katherine R. Kozak, Jack Sadowsky et al. · Bioconjugate Chemistry · 2018 · 76 citations

Medicinal Chemistry, Drug Targeting, Engineering +15

An Antimesothelin-Monomethyl Auristatin E Conjugate with Potent Antitumor Activity in Ovarian, Pancreatic, and Mesothelioma Models

Suzie J. Scales, Nidhi Gupta, Glenn Pacheco et al. · Molecular Cancer Therapeutics · 2014 · 65 citations

Antibody-drug Conjugate Therapy, Immunology, Immunoediting +19