Aimee Fourie-O’Donohue

Author

WuXi AppTec (China)ORCID

Also Known As

Aimee Fourie-O'Donohue, Aimee Fourie-O’Donohue

Publications

770

Citations

H-Index

Concepts

All Affiliations

WuXi AppTec (China)

About

Aimee Fourie-O’Donohue is an author at WuXi AppTec (China) specializing in medicine, pharmacology, and biomolecular engineering.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	437
2	Biomolecular Engineering	3	3	332
3	Biochemistry	2	2	185
4	Engineering	1	1	76
5	Natural Sciences	1	1	109

Aimee Fourie-O’Donohue

Publications

766

Citations

H-Index

Page 1

	Year	Citations
Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody–drug conjugates Leanna R. Staben, Stefan G. Koenig, Sophie M. Lehar, Nature Chemistry Medicinal ChemistryAntibody–drug ConjugatesDrug TargetingMedicineTargeted Drug Delivery	2016	147
High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers Rachana Ohri, Sunil Bhakta, Aimee Fourie-O’Donohue, Bioconjugate Chemistry Molecular BiologyImmunochemistryAntibody EngineeringDisulfide-based LinkersVitro Plasma Stabilities	2018	109
Site-Specific Trastuzumab Maytansinoid Antibody–Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering Thomas H. Pillow, Janet Tien, Kathryn Parsons-Reponte, Journal of Medicinal Chemistry	2014	106
Modulating Antibody–Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification Dian Su, Katherine R. Kozak, Jack Sadowsky, Bioconjugate Chemistry Medicinal ChemistryDrug TargetingEngineeringBiochemistryPolymer-drug Conjugate	2018	76
An Antimesothelin-Monomethyl Auristatin E Conjugate with Potent Antitumor Activity in Ovarian, Pancreatic, and Mesothelioma Models Suzie J. Scales, Nidhi Gupta, Glenn Pacheco, Molecular Cancer Therapeutics Antibody-drug Conjugate TherapyImmunologyImmunoeditingBiological TherapyImmunotherapeutics	2014	65
Attachment Site Cysteine Thiol p<i>K</i><sub>a</sub> Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody–Drug Conjugates Breanna S. Vollmar, BinQing Wei, Rachana Ohri, Bioconjugate Chemistry	2017	45
Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug Conjugates Donglu Zhang, Aimee Fourie-O’Donohue, Peter S. Dragovich, Drug Metabolism and Disposition	2019	41
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates Siddharth Sukumaran, Kapil Gadkar, Crystal Zhang, Pharmaceutical Research Thiomab™ Drug ConjugatesPharmacokinetic ModelingMedicinePharmacologyPhysiologically-based Pharmacokinetic Modeling	2014	40
Total Antibody Quantification for MMAE-Conjugated Antibody–Drug Conjugates: Impact of Assay Format and Reagents Katherine R. Kozak, Siao Ping Tsai, Aimee Fourie-O’Donohue, Bioconjugate Chemistry	2013	33
An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer Sunil Bhakta, Lisa Crocker, Yvonne Chen, Molecular Cancer Therapeutics	2017	31

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